بررسی و مقایسه اثرات 8 هفته تمرینات مقاومتی و استقامتی به همراه مکمل یاری ویتامین D3 بر سایتوکاین های التهابی مردان چاق میانسال مبتلا به پرفشارخونی

Background & Aim: The purpose of this study was to investigate and compare the effects of eight weeks resistance and endurance training with vitamin D3 supplementation on inflammatory cytokines in obese hypertensive middle-aged men. Materials & Methods: Sixty three obese hypertensive middle-aged men (age= 39.85±2.8 years and BMI= 31.6±1.4 kg/m2) volunteered to participate in this study and were randomly divided into six groups of resistance training with vitamin D (R+D, N=11), resistance training with placebo (R+P, N=12), endurance training with vitamin D (E+D, N=9), endurance training with placebo (E+P, N=11), vitamin D (D, N=10) and control (C, N=10, no intervention). The training protocol consisted of endurance training with gradually increasing of duration and intensity and resistance training with 80% of the 1RM, 3 times a week for 8 weeks. The supplement groups consumed daily 3000 IU of vitamin D and the placebo groups ingested the same amount of maltodextrin. Blood pressure and blood samples were measured before starting training protocol and 36 hours after last training sessions. Results: In intervention groups, serum levels of interleukin-8 and interleukin-4 were significantly decreased and increased, respectively. Also, in training groups, systolic and diastolic blood pressure were significantly decreased. Moreover, only in the systolic blood pressure there were significant differences between groups in favor of the E+D group at the post-test. Conclusion: Implementation of endurance and resistance training with vitamin D3 for 8 weeks caused to decreases of blood pressure and inflammation in obese hypertensive men, but the effect of endurance training with vitamin D3 on systolic blood pressure was significantly better.